Glycobiology
Short Mucin-Type O-Glycans in Cancer: Biomarker and Therapeutic Potential amid Analytical Barriers.
Henrique Sousa, Inês A B Ribeiro, Marta Falcão, Daniela F Barreira, Mariana Barbosa, Shally Sharma, Manfred Wuhrer, Noortje de Haan, Paula A Videira
Published: 202510.1093/glycob/cwaf077
Abstract
Mucin-type O-glycans are abundant protein modifications that regulate cell signalling, adhesion, and immune interactions. In cancer, their biosynthetic pathways are frequently disrupted, leading to the accumulation of truncated structures, such as Tn…
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