Genetics
Heterochromatin-based silencing of a foreign tandem repeat in Drosophila melanogaster shows unusual biochemistry and temperature sensitivity.
Tingting Gu, Elena Gracheva, Michael Lee, Wilson Leung, Sophia Bieser, Alixandria Nielsen, Adam T Smiley, Nhi N T Vuong, Matthias Walther, Gunter Reuter, Sarah C R Elgin, Andrew M Arsham
Published: 202510.1093/genetics/iyaf275
Abstract
Eukaryotic genomes are packaged into chromatin, a regulatory nucleoprotein assembly. Establishment, maintenance, and interconversion of chromatin states is required for correct patterns of gene expression, genome integrity, and survival. Transcriptio…
Preview only. Read the full abstract at the source