Genetics
Deletion of Elongator Protein 1 (Elp1) relieves heterochromatin defects in a Pol II mutant of Schizosaccharomyces pombe.
Mamta B Nirmal, Maya E Pearce, Cameron T Liu, Jared M Finkel, Katherine S Darrow, Tommy V Vo
Published: 202510.1093/genetics/iyaf258
Abstract
Heterochromatin is a repressive epigenetic state that suppresses transcription and safeguards genomic integrity. However, the full mechanism of its regulation remains elusive. Here, we focus on a previously described RNA polymerase II (Pol II) varian…
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