G3 (Bethesda, Md.)
Directed evolution for cell separation in natural isolates of budding yeast reveals selection to deactivate AMN1 and the Rim101 pathway in haploids and selection in favor of Hawthorne's deletion in diploids.
Benjamin Galeota-Sprung, Erik Pritchard, Crystal Huang, Amy Fernandez, Paul Sniegowski
Published: 202610.1093/g3journal/jkag011
Abstract
Natural isolates of the yeast Saccharomyces cerevisiae were evolved under a transfer protocol that selected for cell separation and against clumpy growth. Whole-genome sequencing of haploid populations revealed strong selection to deactivate AMN1, a…
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