G3 (Bethesda, Md.)
Identification of an uncharacterized gene as a mitochondrial methionine tRNA-synthetase in Caenorhabditis elegans.
Bharat Vivan Thapa, Mohit Das, David I Taylor, James P Held, Maulik R Patel
Published: 202510.1093/g3journal/jkaf298
Abstract
Aminoacyl-tRNA synthetases (aaRSs) are essential for translation, as they charge tRNA molecules with their corresponding amino acids. Alterations in aaRSs can significantly disrupt both cytosolic and mitochondrial translation. Through a forward genet…
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