European heart journal
Histamine N-methyltransferase upregulation, cardiac hypertrophy, and heart failure.
Jinyan Zhang, Hao Jiang, Liwei Liu, Xin Li, Wenxuan Hong, Lei Xu, Zhen Dong, Zhuocong Xu, Jinfeng Gao, Xiaolei Sun, Wei Luo, Jin Liu, Yu Song, Peng Wang, Jinghong Zhang
Published: 202610.1093/eurheartj/ehaf1065
Abstract
BACKGROUND AND AIMS: Histamine signalling is critical in heart failure (HF). Histamine N-methyltransferase (HNMT) serves as the primary enzyme responsible for histamine clearance in heart, but its role in HF remains undefined. This study investigates…
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