Cardiovascular research
Shorter kidney telomeres are associated with nephrosclerosis by an epigenetic signature.
Olutope Arinola Akinnibosun, Xiaoguang Xu, Amber Emmett, Huy Nguyen, Shadi Hames-Fathi, Maciej Drzal, James Eales, David Scannali, Priscilla R Prestes, Matthew Denniff, Pawel Bogdanski, Joanna Zywiec, Wojciech Wystrychowski, Ewa Zukowska-Szczechowska, Tomasz J Guzik
Published: 202610.1093/cvr/cvag034
Abstract
AIMS: Ageing leads to a progressive loss in structural integrity and a functional decline of human organs, alongside telomere attrition and alterations in DNA methylation patterns. Their relationships in the human kidney in the context of ageing rema…
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