Cardiovascular research
Endothelial Rho kinase controls blood vessel integrity and angiogenesis.
Martin Lange, Caitlin Francis, Jessica Furtado, Jonathan Granger, Young-Bum Kim, James K Liao, Fadi G Akar, Anne Eichmann
Published: 202510.1093/cvr/cvaf246
Abstract
AIMS: The Rho kinases 1 and 2 (ROCK1/2) are serine-threonine specific protein kinases that control actin cytoskeleton dynamics. They are expressed in all cells throughout the body, including cardiomyocytes, smooth muscle cells and endothelial cells (…
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