Cardiovascular research
Transcriptional readthrough at Atf4 locus suppresses Rps19bp1 and impairs heart development.
Zengming Zhang, Tongbin Wu, Zeyu Chen, Danni Chen, Zhengyu Liang, Christopher Adams, Yu Gu, Mao Ye, Fhujjen Barroga, Sylvia Evans, Xiaohai Zhou, Ju Chen
Published: 202510.1093/cvr/cvaf237
Abstract
AIMS: Activating Transcription Factor 4 (ATF4) functions as a transcriptional regulator in various cell types and tissues under both physiological and pathological conditions. While previous studies have linked ATF4 activation with promoting cardiomy…
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