Cardiovascular research
"Loss of circulating glucocorticoid rhythm disrupts the circadian transcriptome and vascular reactivity in the mouse renal artery."
Georgios Krilis, Hannah M Costello, Frances Turner, Robert Little, Anastasiia Komolova, Josselin Nespoux, Alicja Czopek, Donald R Dunbar, Matthew A Bailey, Jess R Ivy
Published: 202510.1093/cvr/cvaf236
Abstract
AIMS: Molecular clocks in the vasculature contribute to the normal circadian blood pressure (BP) rhythm. Glucocorticoids are known to synchronise molecular clocks within peripheral tissues. Disruption of the endogenous glucocorticoid rhythm causes "n…
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