Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
A Phase 1b/2, Randomised, Placebo-controlled Study to Evaluate Safety, Tolerability, Efficacy, and Immunogenicity of VTP-200, a Chimpanzee Adenovirus and Modified Vaccinia Ankara-vectored Multigenotype High-Risk Human Papillomavirus Vaccine in Women with Low-grade Cervical Lesions.
Karin Hellner, Philippe Simon, Philippe De Sutter, Kadri-Liina Vahula, Paula Briggs, Ülle Kiisla, Michelle Russell, Claire Newton, Kobe Dewilde, Katie Anderson, Jakub Kopycinski, Antonella Vardeu, Charlotte Davis, Sarah Sebastian, Raisha Kennerley
Published: 202510.1093/cid/ciaf658
Abstract
BACKGROUND: The clearance of high-risk oncogenic HPV (hrHPV) and related cervical lesions is associated with the development of a robust T cell response. Therapeutic vaccination that induces HPV antigen-specific T cells is a promising approach. METHO…
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