The 2025 Centers for Disease Control and Prevention Non-Occupational HIV Post-Exposure Prophylaxis Guidelines: Updated Regimens and Remaining Questions.

The United States Centers for Disease Control and Prevention recently released updated guidance on non-occupational HIV post-exposure prophylaxis. The guidelines introduce co-formulated antiretrovirals as a preferred regimen, which will likely positively impact prescribing practices and adherence. However, other barriers to access and uptake remain a challenge.