Journal of chromatographic scienceAnimalsTandem Mass SpectrometryDiterpenesRatsChromatography
Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantification of 3,14,19-Triacetyl Andrographolide in Rat Plasma: Application to Preclinical Pharmacokinetic Studies.
Chang Ren, Xin Sui, Kunlin Zhang, Jingjing Wang, Hao Li, Fenghe Yang, Mengjun Zhang, Junli Zhao, Yu Zhang, Guanhua Du, Guang Han
Published: 202510.1093/chromsci/bmaf057
Abstract
3,14,19-triacetyl andrographolide (ADA), a derivative of andrographolide, has emerged as a promising anti-inflammatory compound. In the present study, we established a rapid and sensitive ultra-performance liquid chromatography-tandem mass spectromet…
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