Carcinogenesis
Genomic and transcriptomic characterization of gamma ray- and heavy ion-induced precursor B-cell lymphomas in B6C3F1 mice: Radiation type-dependent interstitial chromosomal deletions at tumor-suppressor gene loci.
Kenta Amano, Hirotaka Tachibana, Chizuru Tsuruoka, Kazuhiro Daino, Takamitsu Morioka, Yi Shang, Atsuko Ishikawa, Tatsuhiko Imaoka, Akira Matsuura, Shizuko Kakinuma
Published: 202610.1093/carcin/bgag002
Abstract
Epidemiological studies have revealed that ionizing radiation is a risk factor for acute lymphoblastic leukemia. Humans can be exposed to radiation via clinical radiotherapies or spaceflight, yet our knowledge of the potential carcinogenic effects of…
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