Brain : a journal of neurology
Dopamine and the dynamics of subthalamic and leg muscle activities in parkinsonian stepping.
Thomas G Simpson, Shenghong He, Laura Wehmeyer, Alek Pogosyan, Fernando Rodriguez Plazas, Ashwini Oswal, Michael G Hart, Rahul S Shah, Harutomo Hasegawa, Christoph Wiest, Sahar Yassine, Xuanjun Guo, Philipp A Loehrer, Anca Merla, Pablo Andrade
Published: 202510.1093/brain/awaf464
Abstract
Freezing of gait (FOG) is a devastating symptom of Parkinson's disease (PD) often resulting in disabling falls and loss of independence. It affects half of patients, yet current therapeutic strategies are insufficient, and the underlying neural mecha…
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