Brain : a journal of neurology
Immune alterations in schizophrenia and the effects of a therapeutic antibody: a neuroimaging study.
Yuya Mizuno, Ines Carreira Figueiredo, Toby Pillinger, Guy Hindley, Luke Baxter, Sita Parmar, Maria C Lobo, Jacek G Donocik, Ivana Rosenzweig, Anish Gupta, Ilaria Callegari, Sami Jeljeli, Joel T Dunn, Alexander Hammers, Ramla Awais
Published: 202510.1093/brain/awaf455
Abstract
Immune dysfunction is implicated in the pathophysiology of schizophrenia. The 18-kDa translocator protein (TSPO), expressed by various cell types including microglia and astrocytes, is widely used as a marker for neuroinflammation and can be quantifi…
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