Brain : a journal of neurologyHumansIronNeurodegenerative DiseasesBrainIron Chelating Agents
Iron on trial: recasting the role of iron in neurodegeneration.
Scott Ayton, Caroline Moreau, David Devos, Ashley I Bush
Published: 202510.1093/brain/awaf398
Abstract
Iron is critical for numerous neurophysiological functions, while its dysregulation is potentially hazardous for neurodegeneration through oxidative stress and ferroptosis. For decades, elevated brain iron levels observed in neurodegenerative disease…
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