The British journal of dermatology
scRNA-seq and Proteomics Uncover Glycolytic Dysregulation Linking Skin and Systemic Inflammation in Dermatomyositis.
Xinzhi Xu, Wenxi Li, Kexin Sun, Feifei Hu, Junxia Huang, Chaofan Liu, Xiuyuan Wang, Jianchao Ge, Ji Yang
Published: 202510.1093/bjd/ljaf486
Abstract
OBJECTIVE: To define the systemic and skin lesion landscape of dermatomyositis (DM) inflammation and investigate pathogenic mechanisms. METHODS: We performed single-cell RNA sequencing (scRNA-seq) on skin lesions from classic adult dermatomyositis pa…
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