The British journal of dermatologyHumansNickelDermatitisAllergic ContactMale
Heterogeneous generation and expansion of epidermal-resident memory T cells in individuals allergic to nickel.
Kelvin Yeung, Julie F Weber, Simone M Stegenborg-Grathwohl, Nuno Bischofberger, Helen Vaher, Jens C B Jacobsen, Frederik N F Sørensen, Konstantin Khodosevich, Jonathan M Coquet, Carsten Geisler, Charlotte M Bonefeld, Lone Skov
Published: 202610.1093/bjd/ljaf427
Abstract
BACKGROUND: Nickel is the most frequent cause of allergic contact dermatitis (ACD). Recent studies have shown that epidermal skin-resident memory T (TRM) cells play a central role in ACD. However, how TRM cells accumulate and differentiate in the epi…
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