Biostatistics (Oxford, England)HumansSingle-Cell AnalysisImmunogenicityVaccineCOVID-19 Vaccines
Determining vaccine responders in the presence of baseline immunity using single-cell assays and paired control samples.
Zhe Chen, Siyu Heng, Asa Tapley, Stephen De Rosa, Bo Zhang
Published: 202410.1093/biostatistics/kxaf045
Abstract
A key objective in vaccine studies is to evaluate vaccine-induced immunogenicity and determine whether participants have mounted a response to the vaccine. Cellular immune responses are essential for assessing vaccine-induced immunogenicity, and sing…
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