Biology of reproduction
RTCB is Essential for Early Mouse Embryogenesis.
Yu-Qi Chen, Mei He, Ran Li, Hai-Xia Hao, Chao Kong, Rui-Tao Zhang, Shu-Lei Liu, Pei-Yan Liu, Hua Ni, Cheng-Qiang He, Nai-Zheng Ding
Published: 202610.1093/biolre/ioag008
Abstract
RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase) is a unique 3'-5' RNA ligase with diverse physiological functions in metazoans. To further explore the role of RTCB in reproduction, we generated a Rtcb conditional knockout mouse model using the Ddx…
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