Biology of reproduction
Injectable contraceptives differentially affect the hypothalamic-pituitary-gonadal axis and amenorrhea incidence†.
Alexis J Bick, Chanel Avenant, Carole-Keza Capitaine, Sharoné Eck, Mu-Tien Lee, Johnson M Moliki, Sigcinile Dlamini, David W Erikson, Jenni Smit, Mags Beksinska, G Justus Hofmeyr, Donita J Africander, Pai-Lien Chen, Janet P Hapgood
Published: 202610.1093/biolre/ioaf292
Abstract
Hormonal contraceptives modulate the hypothalamic-pituitary-ovarian (HPO) axis; however, underlying mechanisms and differences between contraceptives are underexplored. The Women's Health Injectable Contraception and HIV trial randomised 521 women to…
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