Biology of reproduction
Long-term tamoxifen impacts the ovary but not preimplantation embryo development.
Gülbahar Zehra Kutlutürk, Trenton L Place, Michael S Awadalla, Rachel B Danis, Sue Ann Ingles, Isaac Asante, Rita Li, Stan Louie, Frank Z Stanczyk, Lynda K McGinnis
Published: 202510.1093/biolre/ioaf281
Abstract
Many studies have examined the acute effects of chemotherapies and radiation on the ovary; however, few address the impact of long-term chemotherapeutic agents on future reproduction for cancer survivors. The purpose of our study was to determine the…
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