Biology of reproduction
PDK4 is critical for metabolic regulation and progesterone production in bovine granulosa cells.
Xuelian Tao, Dirk Koczan, Julia Brenmoehl, Jens Vanselow, Vijay Simha Baddela
Published: 202510.1093/biolre/ioaf238
Abstract
Non-esterified fatty acids (NEFA) influence ovarian cell function, but the underlying molecular mechanisms remain incompletely understood. Our previous work showed that NEFA induces lipid accumulation and inhibits glucose uptake in bovine granulosa c…
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