Bioinformatics (Oxford, England)
GeoGAD: Geometry-Aware Antibody Design Framework for Complementarity-Determining Region Precision Engineering.
Songjian Wei, Jinxiong Zhang, Yan Chen, Chunyan Tang, Jiayang Tan
Published: 202610.1093/bioinformatics/btag042
Abstract
MOTIVATION: Antibodies, as pivotal effector molecules of the immune system, neutralize pathogens through specific binding to antigens mediated by complementarity-determining regions (CDRs), highlighting the critical importance for precise antibody de…
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