Bioinformatics (Oxford, England)
esloco: simulation-based estimation of local coverage in long-read DNA sequencing.
Adrian Weich, Christopher Lischer, Julio Vera
Published: 202610.1093/bioinformatics/btag009
Abstract
SUMMARY: Long-read DNA sequencing is increasingly applied for whole-genome studies, yet experimental planning often lacks reliable estimates of target region coverage, leading to costly and time-consuming pilot studies and replicates. We present eslo…
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