Bioinformatics (Oxford, England)Deep LearningEpitopesB-LymphocyteSoftwareComputational Biology
RoBep: a region-oriented deep learning model for B-cell epitope prediction.
Yitao Xu, Guanyun Wei, Jingying Zhou, Yuanhua Huang, Weichuan Yu, Zhixiang Lin, Ran Liu, Xiaodan Fan
Published: 202610.1093/bioinformatics/btag006
Abstract
MOTIVATION: Accurate in silico identification of B-cell epitope residues is crucial for antibody design and structure-guided vaccine development. Although recent protein language models and structure-aware methods can capture spatial information of t…
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