Superior antiglycation efficacy of Silymarin from Silybum marianum in Human αA-crystallin: Implications for diabetic cataract prevention.

Hyperglycemia activates the polyol pathway, producing fructose, which promotes glycation and denatures α-crystallin, ultimately leading to diabetic cataracts. This study compared the antiglycation effects of SMR and SBN, using a fructose-induced huma…

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