Bioscience, biotechnology, and biochemistry
Identification and characterization of Dorea ammoniilytica as a novel deoxycholic acid-producing bacterial species in the human gut microbiota.
Ni Wayan Eka Putri Gayatri Kastawa, Yasuhiro Gotoh, Isaiah Song, Tomoya Maeda, Satoru Fukiya
Published: 202510.1093/bbb/zbaf190
Abstract
Deoxycholic acid (DCA), a representative secondary bile acid, is produced by specific gut bacteria through bile acid 7α-dehydroxylation of cholic acid, catalyzed by enzymes encoded in the bai gene operon. Exploration of diversity and functional chara…
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