American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Serum belumosudil concentrations in a patient receiving a combination of 3 gastric acid-suppressing agents: A case report.
Takuya Araki, Hideaki Yashima, Akiko Kaneta, Hisashi Takei, Nobuhiko Kobayashi, Yuri Miyazawa, Yoshiyuki Ogawa, Masashi Kawano, Hiroshi Handa, Koujirou Yamamoto
Published: 202510.1093/ajhp/zxaf270
Abstract
PURPOSE: Belumosudil is an orally administered selective ROCK2 inhibitor used in the treatment of chronic graft-vs-host disease. Given that pharmacological activity has been reported to be concentration dependent, factors affecting absorption must be…
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