American journal of hypertension
Lorundrostat for Patients with Uncontrolled Hypertension: A Systematic Review with Meta-Analysis and Trial Sequential Analysis.
Vicente Morales Ribeiro, Douglas Nunes Cavalcante, Hermes Estevam Torega Celkevicius, Giovanna Cristina Gonçalves Camacho, Henrique Alexsander Ferreira Neves, Kevlin de Souza, Rafael Henkes Machado, Lucca Moreira Lopes, Webster Donaldy, Luiz Aparecido Bortolotto, Jamil Cherem Schneider
Published: 202510.1093/ajh/hpaf246
Abstract
BACKGROUND: The efficacy and safety of lorundrostat, a selective aldosterone synthase inhibitor, in patients with uncontrolled hypertension remain unclear. This meta-analysis aimed to evaluate its effects on blood pressure and risk of hyperkalemia. M…
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