American journal of clinical pathologyHumansLimit of DetectionRegression AnalysisSensitivity and SpecificityModels
Sensitivity analysis of limit of detection estimation using probit regression.
Kathleen E Angell, Dylan S George, M Jana Broadhurst, David M Brett-Major
Published: 202510.1093/ajcp/aqaf123
Abstract
OBJECTIVE: Our objective was to explore how variations in the number and distribution of tested concentrations around the presumed lower limit of detection (LLOD) affect the estimate and its confidence interval. METHODS: We reviewed published LLOD ev…
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