Molecular biology of the cellAnimalsMitophagyDrosophila ProteinsMitochondriaUbiquitin
Kenny mediates the recruitment of the phagophore for ubiquitin-dependent mitophagy in Drosophila neurons.
Hubert Osei Acheampong, Emily Rozich, Zachary Haupt, Charlee Tokarz, Mousumee Khan, Zahraa A Ghosn, Ryan Insolera
Published: 202610.1091/mbc.E25-05-0235
Abstract
The maintenance of healthy mitochondria is essential to neuronal homeostasis. Mitophagy is a critical mechanism that degrades damaged mitochondria, and disruption of this process is associated with neurodegenerative disease. Previous work has shown t…
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