BiofabricationAnimalsOrganoidsHumansHematopoietic Stem CellsMice
Engineering an organoid culture system for enhanced murine and human hematopoietic stem and progenitor cell self-renewal and expansion.
Keyi Chen, Yunqiao Li, Xuan Tang, Caiping Xu, Yunxing Li, Xumin Wu, Jisheng Li, Bowen Zhang, Jiahui Zhao, Tao Fan, Lijuan He, Xuetao Pei, Yanhua Li
Published: 202510.1088/1758-5090/ae175f
Abstract
Developing a biomimetic culture system is crucial for the efficient maintenance and expansion of rare hematopoietic stem and progenitor cells (HSPCs)in vitro. This advancement can significantly enhance the application of HSPC-based transplantation th…
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