Physics in medicine and biology
How chain length influences x-ray-induced fragmentation of iodine-doped DNA oligomers.
Ouassim Hocine Hafiani, Friederike Krüger, Marta Berholts, Lucas Schwob, Bo Stenerlöw, Tomas André, Oscar Granas, Nicusor Timneanu, Juliette Leroux, Aarathi Nair, Laura Pille, Bart Oostenrijk, Sadia Bari, Olle Björneholm, Carl Caleman
Published: 202610.1088/1361-6560/ae35c4
Abstract
OBJECTIVE: Incorporating iodine into DNA bases offers a strategy to enhance radiotherapy. The iodine increases the photoabsorption cross‑section and can promote DNA disruption and cell death in cancerous tissue. In this study, we investigate the loca…
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