Physics in medicine and biologyHumansRadiotherapy DosageLung NeoplasmsRadiotherapy PlanningComputer-Assisted
Mitigating the impact of FLASH-model uncertainties through personalized FLASH optimization functions for delivery pattern optimization for lung IMPT.
Manon C van Zon, Sebastiaan Breedveld, Mischa S Hoogeman, Steven J M Habraken
Published: 202610.1088/1361-6560/ae2f16
Abstract
Objective.It is generally assumed that the FLASH effect is triggered at dose rates (DRs) of at least 40 Gy s-1, while recent studies indicate that this threshold is not binary but follows a sigmoid across samples. Some patients may thus already exper…
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