The Journal of experimental medicineHumansLymphocyte ActivationLigandsMucosal-Associated Invariant T CellsAnimals
CD2 and its ligands are involved in development and activation of MAIT cells.
Kaiwen Zhu, Jiayu Dou, Bin Li, Jin Qian, Ming-Chao Zhong, Zhenghai Tang, Yan Lu, André Veillette
Published: 202510.1084/jem.20250431
Abstract
MAIT cells are innate-like T cells known for their semi-invariant TCR that recognizes vitamin B metabolites presented by MR1. While the involvement of TCR and cytokines in development and activation of MAIT cells is well documented, the contribution…
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