The Journal of experimental medicineAnimalsInterleukin-10LungImmunityInnate
Lung tissue-resident memory T cells optimize protection by IL-10 regulation of innate immunity.
Alexander Y Yang, Julia Davis-Porada, Daniel H Paik, Alex B George, Brea H Brown, Paige L Ruschke, Peter A Sims, Ziv Frankenstein, Anjali Saqi, Donna L Farber
Published: 202610.1084/jem.20242307
Abstract
Respiratory viral infections establish tissue-resident memory T cells (TRM) in the lung, which provide optimal protection against subsequent infections, though the underlying mechanisms are incompletely understood. Here, we demonstrate in a mouse mod…
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