Journal of environmental science and health. Part C, Toxicology and carcinogenesis
Environmental determinants of therapeutic drug failure: a systematic review of heavy metal-induced inefficacy.
James O Ibibama, Godswill J Udom, Rehoboth Uwaga, Unique Chukwu, Margaret Azaatse, Chinwe Leonard-Alika, Omunakwe Onu, Samuel Saka, Chiara Frazzoli, Orish Ebere Orisakwe
Published: 202610.1080/26896583.2025.2611653
Abstract
Therapeutic drug failure poses a significant global health burden, particularly in developing regions with high environmental toxicant exposure. While traditionally attributed to factors such as substandard drugs, genetic polymorphisms, and non-compl…
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