Amyotrophic lateral sclerosis & frontotemporal degeneration
Unraveling the genetic landscape of ALS in Greece: identification of known and novel causative variants in a 353-patient cohort.
Chrisoula Kartanou, Zoi Kontogeorgiou, Theodoros Loupis, Dimitrios M Vrachnos, Nikolaos Ragazos, Ifigenia Spyropoulou, Maria Petraki, Chrysoula Koniari, Stavroula Aristeidou, Eleftheria Koropouli, Ariadne Daponte, Michail Rentzos, Elisabeth Kapaki, Marios Panas, Periklis Makrythanasis
Published: 202510.1080/21678421.2025.2582828
Abstract
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is an adult-onset, progressive, fatal neurodegenerative disorder characterized by progressive loss of motor neurons. Approximately 15% of individuals diagnosed with ALS have a known genetic variant that…
Preview only. Read the full abstract at the source