mAbsReceptorsIgGHumansAnimalsMice
Extracellular domain 1 of human FcγRI (CD64) identified as the binding site for anti-FcγRI antibodies.
Tosca Holtrop, Elsemieke M Passchier, Sophie O'Toole, W Joost Kraan, Kevin Budding, Jeanette H W Leusen
Published: 202510.1080/19420862.2025.2580695
Abstract
FcγRI (CD64) is the only Fcγ receptor capable of high-affinity binding to monomeric IgG and found on monocytes, macrophages, eosinophils, neutrophils, and dendritic cells. FcγRI contains three C2-type immunoglobulin (Ig) extracellular domains (EC1-3)…
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