Systems biology in reproductive medicineMaleAnimalsSpermatozoaCattleHumans
A novel sperm FcR binding assay that assesses sperm fertilizing potential.
Barb Cohen, John Walsh, Zimu Chen, Sergey Moskovtsev, Erin Schnellinger, Marty Kathrins, H Nadir Ciray, Larry Lipshultz, Paul Turek, Clifford Librach
Published: 202510.1080/19396368.2025.2590747
Abstract
Freshly ejaculated mammalian sperm have poor fertilizing ability, with fertility only gained after sperm undergo capacitation and the acrosome reaction. To visualize exposed Fc receptors (FcRs), which occur during the acrosome reaction and whose abse…
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