Bioanalysis
Addressing nonspecific interactions in a Gyrolab anti-drug antibody (ADA) assay: a case study on method optimization to improve repeatability.
Eliza Kęsy-Siwik, John Chappell, Dorota Jaros, Małgorzata Urbaniak, Agata Sakowicz
Published: 202510.1080/17576180.2025.2601860
Abstract
AIM: Anti-drug antibodies (ADAs) can impact drug efficacy and safety, necessitating sensitive and drug-tolerant assays for accurate detection. The main goal of the study was re-optimization of the Gyrolab immunoassay intended to detect ADAs against M…
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