Future medicinal chemistry
Exploring the in vitro urease inhibitory potential, molecular docking and dynamics simulations investigation of mefenamic acid derivatives.
Obaid Ullah, Aftab Alam, Muhammad Ayaz, Najeeb Ur Rehman, Atta Ullah, Ahmed A Elhenawy, Ajmal Khan, Ahmed Al-Harrasi, Mumtaz Ali, Manzoor Ahmad
Published: 202610.1080/17568919.2026.2619465
Abstract
AIMS: To biologically evaluate a series of hydrazide derivatives of mefenamic acid as anti-urease agents, elucidating their mechanism of action through integrated computational and experimental approaches. METHOD: The inhibitory mechanism was interpr…
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