Epigenomics
E2F1-driven cholesterol synthesis via the SND1/ACLY axis potentiates malignant progression in prostate cancer.
Xiaopeng Zheng, Chengru Yang, Deqiang Bian, Guoxin Shi, Li Wang, Xiaohan Li, Yufei Chen, Hua Xin, Liming Wang
Published: 202610.1080/17501911.2026.2617186
Abstract
AIM: This study aimed to clarify the mechanisms of E2F transcription factor 1 (E2F1) in the Cholesterol (CHOL) synthesis of Prostate cancer (PCa). METHODS: CHOL component content was detected using a commercial test kit. The interaction between E2F1…
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