The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological PsychiatryAnimalsMaleHippocampusMiceDepression
Environmental enrichment by targeting hippocampal claudins attenuates depressive-like behaviours in maternally separated male mice.
Mehdi Ansari, Shima Balali-Dehkordi, Mohammad Rahimi-Madiseh, Elham Zarean, Hossein Amini-Khoei
Published: 202610.1080/15622975.2025.2577759
Abstract
OBJECTIVES: Maternal separation (MS) is a well-established risk factor for psychological disorders like depression. Alterations in the blood-brain barrier (BBB) and its tight junction proteins, such as claudins (CLDNs), may contribute to the pathophy…
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