Clinical toxicology (Philadelphia, Pa.)AcetylcysteineHumansAcetaminophenAntidotesDrug Overdose
We need a standardized North American acetylcysteine dosing regimen for the treatment of paracetamol (acetaminophen) poisoning.
Milton Tenenbein
Published: 202610.1080/15563650.2025.2571457
Abstract
INTRODUCTION: Acetylcysteine is the antidote for paracetamol (acetaminophen) poisoning. Prescott and colleagues introduced it in the 1970s as a three-infusion regimen. This regimen became standard care for several decades. Its efficacy is accepted, t…
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