Autophagy
Cerebral FURIN deficiency impairs astrocytic lipophagy through ITGAV maturation.
Xiao-Yong Xie, Lu Wang, Shi-Qi Xie, Gui-Feng Zhou, Qi-Xin Wen, Yuan-Lin Ma, Qi-Lei Zhang, Xiao-Xin Yan, Biao Luo, Jian Chen, Li Song, Xue Chen, Chen-Lu Li, Qiu-Ling Pan, Yue Liu
Published: 202510.1080/15548627.2025.2601039
Abstract
FURIN cleaves a subset of proproteins into functional mature fragments. Evidence suggests that FURIN is involved in brain development and the associated diseases, whereas the potential mechanisms remain incompletely understood. Here, we report that c…
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