Journal of pain & palliative care pharmacotherapy
Evidence Supporting Alternative Parenteral Routes of Opioid Administration for Pain Management in Sickle Cell Disease: A Comprehensive Review.
Nkem P Nonyel, Victoria Hannahoe, Earnestradj Porselvame
Published: 202510.1080/15360288.2025.2574471
Abstract
Sickle cell disease (SCD) is an autosomal, recessive, genetic disorder that affects the structure and function of the hemoglobin. Pain is the hallmark of SCD, and opioids and nonsteroidal anti-inflammatory drugs are the mainstay of SCD pain control d…
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