Tribute to Paul F. Torrence, a brilliant chemist switching from polynucleotides to nucleosides, oligonucleotides, and back to nucleosides.

Via Dr. Bernhard Witkop, I generated the interest of Dr. Paul F. Torrence to evaluate the requirements of synthetic polynucleotides to induce interferon. His interest, akin to mine, then shifted to 5-substituted 2'-deoxyuridines, which we first evalu…

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